Autologous Stem Cell Activation

What is Platelet-rich plasma?

Platelet-rich plasma is a concentration of platelets in plasma developed by gradient density centrifugation. It contains many growth factors, such as Platelet-derived growth factor (PDGF), transforming growth factor beta (TGFB), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), insulin-like growth factor (IGF), and it has been successfully used in a variety of clinical applications for improving hard and soft tissue healing. Platelet-rich plasma has also been shown to enhance the proliferation of human Adult Stem Cells

Stem Cells and Platelet-Rich Plasma Stem Cell Activation

An important point to note is that there is no debate that freshly isolated Adult Stem Cells which have not been activated are essentially useless as opposed to Adult Stem Cells which have undergone proper activation.

In platelet-rich plasma applications Growth Factors  from the patient’s own circulating blood platelets are used to activate the Adult Stem Cells harvested from the same patient.

Healing is a complex process, involving a mechanism of complex cascading regulatory events at both the molecular and cellular levels.  Growth factors are secreted by a wide variety of cells to regulate the wound healing process in an orderly manner. Over the last decade, various Growth factors, including platelet-derived growth factor have been used to accelerate the healing process.